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ampk signaling phosphorylation antibody array  (Full Moon BioSystems)

 
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    Structured Review

    Full Moon BioSystems ampk signaling phosphorylation antibody array
    Metrnl activates the <t>LKB1/AMPK</t> signaling in cardiomyocytes . ( A ) Heatmap showing the effects of Metrnl on the components of AMPK array. ( B ) Top ten signaling protein induced by Metrnl. ( C ) Metrnl dose- and time-dependently induced <t>AMPK</t> <t>phosphorylation.</t> ( D ) Effects of Metrnl on HG-induced downregulation of phosphorylated AMPK. ( E ) Effects of Metrnl shRNA on HG-induced downregulation of phosphorylated AMPK. ( F ) Cardiomyocytes were pretreated with STO-609 (0.8 μM) or Takinib (10 mM) for 30 min, and challenged by Metrnl (0.2 μg/ml) for 30 min, and then stimulated for HG for 48 h. Cardiomyocytes were pretreated with LKB1 siRNA (100 nM) for 6 h, and challenged by Metrnl (0.2 μg/ml) for 30 min, and then stimulated for HG for 48 h. Western blot was used to determine phosphorylated AMPK. ( G ) Effects of Metrnl on HG-induced downregulation of phosphorylated LKB1. ( H ) Effects of Metrnl shRNA on HG-induced downregulation of phosphorylated LKB1. n = 4. * P < 0.05 versus 0 μg/ml, 0 min, NG, Con, Con shRNA, † P < 0.05 versus HG + Con shRNA, Metrnl or HG.
    Ampk Signaling Phosphorylation Antibody Array, supplied by Full Moon BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ampk signaling phosphorylation antibody array/product/Full Moon BioSystems
    Average 90 stars, based on 1 article reviews
    ampk signaling phosphorylation antibody array - by Bioz Stars, 2026-03
    90/100 stars

    Images

    1) Product Images from "Metrnl ameliorates diabetic cardiomyopathy via inactivation of cGAS/STING signaling dependent on LKB1/AMPK/ULK1-mediated autophagy"

    Article Title: Metrnl ameliorates diabetic cardiomyopathy via inactivation of cGAS/STING signaling dependent on LKB1/AMPK/ULK1-mediated autophagy

    Journal: Journal of Advanced Research

    doi: 10.1016/j.jare.2022.10.014

    Metrnl activates the LKB1/AMPK signaling in cardiomyocytes . ( A ) Heatmap showing the effects of Metrnl on the components of AMPK array. ( B ) Top ten signaling protein induced by Metrnl. ( C ) Metrnl dose- and time-dependently induced AMPK phosphorylation. ( D ) Effects of Metrnl on HG-induced downregulation of phosphorylated AMPK. ( E ) Effects of Metrnl shRNA on HG-induced downregulation of phosphorylated AMPK. ( F ) Cardiomyocytes were pretreated with STO-609 (0.8 μM) or Takinib (10 mM) for 30 min, and challenged by Metrnl (0.2 μg/ml) for 30 min, and then stimulated for HG for 48 h. Cardiomyocytes were pretreated with LKB1 siRNA (100 nM) for 6 h, and challenged by Metrnl (0.2 μg/ml) for 30 min, and then stimulated for HG for 48 h. Western blot was used to determine phosphorylated AMPK. ( G ) Effects of Metrnl on HG-induced downregulation of phosphorylated LKB1. ( H ) Effects of Metrnl shRNA on HG-induced downregulation of phosphorylated LKB1. n = 4. * P < 0.05 versus 0 μg/ml, 0 min, NG, Con, Con shRNA, † P < 0.05 versus HG + Con shRNA, Metrnl or HG.
    Figure Legend Snippet: Metrnl activates the LKB1/AMPK signaling in cardiomyocytes . ( A ) Heatmap showing the effects of Metrnl on the components of AMPK array. ( B ) Top ten signaling protein induced by Metrnl. ( C ) Metrnl dose- and time-dependently induced AMPK phosphorylation. ( D ) Effects of Metrnl on HG-induced downregulation of phosphorylated AMPK. ( E ) Effects of Metrnl shRNA on HG-induced downregulation of phosphorylated AMPK. ( F ) Cardiomyocytes were pretreated with STO-609 (0.8 μM) or Takinib (10 mM) for 30 min, and challenged by Metrnl (0.2 μg/ml) for 30 min, and then stimulated for HG for 48 h. Cardiomyocytes were pretreated with LKB1 siRNA (100 nM) for 6 h, and challenged by Metrnl (0.2 μg/ml) for 30 min, and then stimulated for HG for 48 h. Western blot was used to determine phosphorylated AMPK. ( G ) Effects of Metrnl on HG-induced downregulation of phosphorylated LKB1. ( H ) Effects of Metrnl shRNA on HG-induced downregulation of phosphorylated LKB1. n = 4. * P < 0.05 versus 0 μg/ml, 0 min, NG, Con, Con shRNA, † P < 0.05 versus HG + Con shRNA, Metrnl or HG.

    Techniques Used: shRNA, Western Blot



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    ampk signaling phosphorylation antibody array  (Full Moon BioSystems)
    90
    Full Moon BioSystems ampk signaling phosphorylation antibody array
    Metrnl activates the <t>LKB1/AMPK</t> signaling in cardiomyocytes . ( A ) Heatmap showing the effects of Metrnl on the components of AMPK array. ( B ) Top ten signaling protein induced by Metrnl. ( C ) Metrnl dose- and time-dependently induced <t>AMPK</t> <t>phosphorylation.</t> ( D ) Effects of Metrnl on HG-induced downregulation of phosphorylated AMPK. ( E ) Effects of Metrnl shRNA on HG-induced downregulation of phosphorylated AMPK. ( F ) Cardiomyocytes were pretreated with STO-609 (0.8 μM) or Takinib (10 mM) for 30 min, and challenged by Metrnl (0.2 μg/ml) for 30 min, and then stimulated for HG for 48 h. Cardiomyocytes were pretreated with LKB1 siRNA (100 nM) for 6 h, and challenged by Metrnl (0.2 μg/ml) for 30 min, and then stimulated for HG for 48 h. Western blot was used to determine phosphorylated AMPK. ( G ) Effects of Metrnl on HG-induced downregulation of phosphorylated LKB1. ( H ) Effects of Metrnl shRNA on HG-induced downregulation of phosphorylated LKB1. n = 4. * P < 0.05 versus 0 μg/ml, 0 min, NG, Con, Con shRNA, † P < 0.05 versus HG + Con shRNA, Metrnl or HG.
    Ampk Signaling Phosphorylation Antibody Array, supplied by Full Moon BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ampk signaling phosphorylation antibody array/product/Full Moon BioSystems
    Average 90 stars, based on 1 article reviews
    ampk signaling phosphorylation antibody array - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    ampk signaling phosphorylation antibody array pam174  (Full Moon BioSystems)
    90
    Full Moon BioSystems ampk signaling phosphorylation antibody array pam174
    Metrnl activates the <t>LKB1/AMPK</t> signaling in cardiomyocytes . ( A ) Heatmap showing the effects of Metrnl on the components of AMPK array. ( B ) Top ten signaling protein induced by Metrnl. ( C ) Metrnl dose- and time-dependently induced <t>AMPK</t> <t>phosphorylation.</t> ( D ) Effects of Metrnl on HG-induced downregulation of phosphorylated AMPK. ( E ) Effects of Metrnl shRNA on HG-induced downregulation of phosphorylated AMPK. ( F ) Cardiomyocytes were pretreated with STO-609 (0.8 μM) or Takinib (10 mM) for 30 min, and challenged by Metrnl (0.2 μg/ml) for 30 min, and then stimulated for HG for 48 h. Cardiomyocytes were pretreated with LKB1 siRNA (100 nM) for 6 h, and challenged by Metrnl (0.2 μg/ml) for 30 min, and then stimulated for HG for 48 h. Western blot was used to determine phosphorylated AMPK. ( G ) Effects of Metrnl on HG-induced downregulation of phosphorylated LKB1. ( H ) Effects of Metrnl shRNA on HG-induced downregulation of phosphorylated LKB1. n = 4. * P < 0.05 versus 0 μg/ml, 0 min, NG, Con, Con shRNA, † P < 0.05 versus HG + Con shRNA, Metrnl or HG.
    Ampk Signaling Phosphorylation Antibody Array Pam174, supplied by Full Moon BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ampk signaling phosphorylation antibody array pam174/product/Full Moon BioSystems
    Average 90 stars, based on 1 article reviews
    ampk signaling phosphorylation antibody array pam174 - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Metrnl activates the LKB1/AMPK signaling in cardiomyocytes . ( A ) Heatmap showing the effects of Metrnl on the components of AMPK array. ( B ) Top ten signaling protein induced by Metrnl. ( C ) Metrnl dose- and time-dependently induced AMPK phosphorylation. ( D ) Effects of Metrnl on HG-induced downregulation of phosphorylated AMPK. ( E ) Effects of Metrnl shRNA on HG-induced downregulation of phosphorylated AMPK. ( F ) Cardiomyocytes were pretreated with STO-609 (0.8 μM) or Takinib (10 mM) for 30 min, and challenged by Metrnl (0.2 μg/ml) for 30 min, and then stimulated for HG for 48 h. Cardiomyocytes were pretreated with LKB1 siRNA (100 nM) for 6 h, and challenged by Metrnl (0.2 μg/ml) for 30 min, and then stimulated for HG for 48 h. Western blot was used to determine phosphorylated AMPK. ( G ) Effects of Metrnl on HG-induced downregulation of phosphorylated LKB1. ( H ) Effects of Metrnl shRNA on HG-induced downregulation of phosphorylated LKB1. n = 4. * P < 0.05 versus 0 μg/ml, 0 min, NG, Con, Con shRNA, † P < 0.05 versus HG + Con shRNA, Metrnl or HG.

    Journal: Journal of Advanced Research

    Article Title: Metrnl ameliorates diabetic cardiomyopathy via inactivation of cGAS/STING signaling dependent on LKB1/AMPK/ULK1-mediated autophagy

    doi: 10.1016/j.jare.2022.10.014

    Figure Lengend Snippet: Metrnl activates the LKB1/AMPK signaling in cardiomyocytes . ( A ) Heatmap showing the effects of Metrnl on the components of AMPK array. ( B ) Top ten signaling protein induced by Metrnl. ( C ) Metrnl dose- and time-dependently induced AMPK phosphorylation. ( D ) Effects of Metrnl on HG-induced downregulation of phosphorylated AMPK. ( E ) Effects of Metrnl shRNA on HG-induced downregulation of phosphorylated AMPK. ( F ) Cardiomyocytes were pretreated with STO-609 (0.8 μM) or Takinib (10 mM) for 30 min, and challenged by Metrnl (0.2 μg/ml) for 30 min, and then stimulated for HG for 48 h. Cardiomyocytes were pretreated with LKB1 siRNA (100 nM) for 6 h, and challenged by Metrnl (0.2 μg/ml) for 30 min, and then stimulated for HG for 48 h. Western blot was used to determine phosphorylated AMPK. ( G ) Effects of Metrnl on HG-induced downregulation of phosphorylated LKB1. ( H ) Effects of Metrnl shRNA on HG-induced downregulation of phosphorylated LKB1. n = 4. * P < 0.05 versus 0 μg/ml, 0 min, NG, Con, Con shRNA, † P < 0.05 versus HG + Con shRNA, Metrnl or HG.

    Article Snippet: The cell lysates from four-independent cell samples in each group were collected for the antibody array experiments using an AMPK signaling phosphorylation antibody array (PAM174, Full Moon Biosystems, Sunnyvale, USA).

    Techniques: shRNA, Western Blot